Impact of a Ketogenic Weight-reduction plan versus a Mediterranean Weight-reduction plan on HbA1c in People with Prediabetes and Sort 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial
Proper off the bat, I do not like that they studied each diabetes and prediabetics. There have been solely 40 unique research contributors, with full knowledge on solely 33. Why lump the 2 collectively?
Individuals adopted every eating regimen for 12 weeks then lab knowledge and physique weight had been assessed.
The researchers conclusions:
HbA1c [a measure of blood sugar control] was not completely different between eating regimen phases after 12-weeks, however improved from baseline on each diets, possible resulting from a number of shared dietary facets. WFKD [ketogenic diet] was useful for better lower in triglycerides, but in addition had potential untoward dangers from elevated LDL-C, and decrease nutrient intakes from avoiding legumes, fruits, and complete intact grains, in addition to being much less sustainable.
Triglycerides dropped extra on the keto eating regimen, no shock. Physique weight dropped the identical for each diets, 7-8%. HDL-cholesterol (the “good ldl cholesterol”) rose 11% on keto and seven% on the Mediterranean eating regimen. HgbA1c dropped the identical on each diets, about 8% from baseline. Each diets result in consuming ~300 energy much less per day than baseline consumption.
Dr Bret Scher addressed the elevated LDL-cholesterol (aka “dangerous ldl cholesterol”) over at DietDoctor.com:
The authors reported that LDL “dangerously” rose 10% on the keto eating regimen. However was it actually a harmful change? Triglycerides went down on the keto eating regimen, as we’d anticipate. And as we noticed in 2018 with the Virta Well being trial, on common, LDL went up 10%. Nonetheless, the calculated cardiac danger rating went down 12%.
When it comes to answering the headline query, Keto Versus Mediterranean Weight-reduction plan: Which Is Finest for T2 Diabetics and Prediabetics?, the reply actually relies on long-term knowledge regarding longevity and varied illnesses. This research does not reply the query.
What say you?
Steve Parker, MD
